Delivering a Hard Blow Against Norovirus
Norovirus, often known as stomach flu, is so good at infecting humans that it’s been called the perfect human pathogen, so virulent that a person can become sick within a few hours of consuming as few as 20 virus particles. In the United States alone, there are about 21 million cases each year that result in more than 800 deaths. The NoroCORE team, led by North Carolina State University, is a multi-disciplinary collaborative of 30 researchers who are leaders in the fields of basic, food, and environmental virology from 25 universities. Their goal was to reduce the burden of foodborne illness associated with viruses. NIFA supports the project with a $25 million CAP grant. In 2016, NoroCORE team members at the Baylor College of Medicine announced that they had successfully cultured the human norovirus in intestinal cells. This goal had eluded scientists for over 48 years. This discovery can lead to advances in the development of vaccines, therapeutics, and other measures to control the virus in humans and also affect management of norovirus transmission.
NIFA originally published this impact in the NIFA 2016 Annual Report. Want to read about more impacts like this? Check out Fresh from the Field, a weekly bulletin showcasing transformative impacts made by grantees funded by NIFA.